Cancer Immunotherapy via Targeting Cancer Stem Cells Using Vaccine Nanodiscs

Hassani Najafabadi A, Zhang J, Aikins ME, Najaf Abadi ZI, Liao F, Qin Y, Okeke EB, Scheetz LM, Nam J, Xu Y, Adams D, Lester P, Hetrick T, Schwendeman A, Wicha MS, Chang AE, Li Q, and Moon JJ. 

Nano Letters doi.org/10.1021/acs.nanolett.0c03414, 2020

Robust Anti‐Tumor T Cell Response with Efficient Intratumoral Infiltration by Nanodisc Cancer Immunotherapy

Kuai R, Singh PB, Sun X, Xu C, Najafabadi Hassani A, Scheetz L, Yuan W, Xu Y, Hong H, Keskin DB, Wu CJ, Jain R, Schwendeman A, and Moon JJ

Advanced Therapeutics. doi: 10.1002/adtp.202000094, 2020

Synthetic high-density lipoprotein nanodiscs for personalized immunotherapy against gliomas

Scheetz L, Kadiyala P, Sun X, Son S, Najafabadi AH, Aikins, M, Lowenstein PR, Schwendeman A, Castro MG, and Moon JJ 

Clinical Cancer Research, doi: 10.1158/1078-0432.CCR-20-0341, 2020

High-Density Lipoprotein-Mimicking NanoDiscs for Chemo-immunotherapy against Glioblastoma Multiforma

Padma Kadiyala, Dan Li, Fernando M. Nuñez, David Altshuler, Robert Doherty, Rui Kuai, Minzhi Yu, Neha Kamran,  Marta Edwards, James J. Moon, Pedro R. Lowenstein, Maria G. Castro, Anna Schwendeman

ACS NANO 2019, 13, 1365-1384

Cancer Nanomedicine for Combination Cancer Immunotherapy

Jutaek Nam, Sejin Son, Kyung Soo Park, Weiping Zou, Lonnie D. Shea, and James J. Moon

Nature Reviews Materials. Vol. 4, 398-414, June 2019

Engineering Patient-Specific Cancer Immunotherapies

Lindsay Scheetz, Kyung Soo Park, Qiao Li, Pedro R. Lowenstein, Maria G. Castro, Anna Schwendeman, and

James J. Moon

Nature Biomedical Engineering August 2019

Elimination of Established Tumors with Nanodisc-based Combination Chemoimmunotherapy

Kuai R, Yuan W, Son S, Nam J, Xu Y, Fan Y, Schwendeman A, and Moon JJ

Science Advances. 4, eaao1736, 2018

Subcutaneous Nanodisc Vaccination with Neoantigens for Combination Cancer Immunotherapy

Kuai R, Sun X, Yuan W, Xu Y, Schwendeman A and Moon JJ

Bioconjugate Chemistry. 29 (3), 771-775, 2018

Designer Vaccine Nanodiscs for Personalized Cancer Immunotherapy

Kuai R, Ochyl LJ, Bahjat KS, Schwendeman A and Moon JJ

Nature Materials. 16 (4), 489-496, 2017

High-density Lipoproteins: Nature’s Multifunctional Nanoparticles

Kuai R, Li D, Chen YE, Moon JJ, and Schwendeman A

ACS NANO. 10, 3, 3015-41, 2016

Lipid-Based Nanoparticles Vaccine Applications

Kuai R, Ochyl LJ, Schwendeman A, and Moon JJ

Biomedical Engineering: Frontier Research and Converging Technologies, Springer, Edited by Drs. Jo, Jun, Shin, and Lee. 9, 177-197, 2015